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DeCS
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Descriptor English:
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Nucleic Acid Denaturation
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Descriptor Spanish:
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desnaturalización de ácidos nucleicos
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Descriptor Portuguese:
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Desnaturação de Ácido Nucleico
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Synonyms English:
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Acid Denaturation, Nucleic
DNA Denaturation
DNA Melting
Denaturation, DNA
Denaturation, Nucleic Acid
Denaturation, RNA
Nucleic Acid Denaturations
RNA Denaturation
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Tree Number:
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E05.393.640
G02.111.603
G05.627
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Definition English:
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Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible. |
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Indexing Annotation English:
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IM general only; coord NIM with DNA or RNA or specific (IM)
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See Related English:
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RNA Stability
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History Note English:
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70(67)
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Allowable Qualifiers English:
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Record Number:
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9878
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Unique Identifier:
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D009691
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Occurrence in VHL:
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Similar:
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DeCS
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